Transposable multiresistance

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Nutrition and Multiresistance Alert

In the last 70 years, the advent of antibiotics radically changed human life, avoiding epidemic infections caused by microbial agents on mankind and loss of enormous quantity of food. Nowadays, most of antibiotics are used in intensive livestock. Furthermore, the contamination of food and spoilage by microorganisms is a major concern to consumers, government authorities and food industries. The...

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Tn2424, a multiresistance transposon 25 kilobases long, was isolated from IncFII plasmid NR79. Tn2424 transposed resistance to sulfonamides, streptomycin and spectinomycin, mercuric chloride, chloramphenicol, and amikacin with a frequency of 6 X 10(-5). Resistance to amikacin was mediated by a 6'-N-acetyltransferase, which conferred higher levels of resistance in Pseudomonas aeruginosa than in ...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 1985

ISSN: 0305-7453,1460-2091

DOI: 10.1093/jac/16.4.416